3,4-Dihydro-6,7-dimethoxyisoquinoline → HCID 13562961, compound

HRID 2118514Notes

Reaction equation

HRID 2118514 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[CH:9]=[N:8][CH2:7][CH2:6]2.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH:22]=[C:23]([O:27][CH3:28])[C:24]=1[O:25][CH3:26])[CH2:20][Cl:21]>O1CCOCC1>[Cl-:21].[CH3:28][O:27][C:23]1[CH:22]=[C:19]([CH:18]=[C:17]([O:16][CH3:15])[C:24]=1[O:25][CH3:26])[CH2:20][N+:8]1[CH2:7][CH2:6][C:5]2[C:10](=[CH:11][C:12]([O:13][CH3:14])=[C:3]([O:2][CH3:1])[CH:4]=2)[CH:9]=1

Participants

4

Reactant 2

HCID 300583,4-Dihydro-6,7-dimethoxyisoquinolineHCID 774485-(Chloromethyl)-1,2,3-trimethoxybenzene

Product 1

HCID 13562961HCID 13562961, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The title compound is prepared analogously to Example A from 6,7-dimethoxy-3,4-dihydroisoquinoline and 3,4,5-trimethoxybenzyl chloride in dioxan. Melting point: 187°-189° C. (Decomp.)

Sources & evidence

ORD record
ord-e9a1d006d0e94705a113efc01067157a
Source dataset
uspto-grants-1987_07
Patent number
US04678792

Reaction notes

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