HuagongsheHuagongshe Chemistry Print Report · For research reference only
Picolinic acid → HCID 2754831, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Picolinic acid | HCID 1018 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | N-Hydroxysuccinimide | HCID 80170 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 2754831 | HCID 2754831 | — |
Reaction Steps
The N-picolinoyloxysuccinimide is prepared by adding 8.4 g of N,N'-dicyclohexylcarbodiimide to a solution of 5.0 g of picolinic acid and 4.7 g of N-hydroxysuccinimide in 50 ml of dimethylformamide. The mixture is stirred overnight, triturated with ether and recrystallized from ethyl acetate, methylene chloride (1:1). The solid is collected and dried; mp. 174°-175°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04678800 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-4abad34ebded45dfac07cbee404756e9 |
| Source note | uspto-grants-1987_07 |