反应详情

The starting material was prepared by reaction of 2-chloroimidazole with t-butyl bromoacetate in CH2Cl2 /aqueous sodium hydroxide in presence of tetra-n-butyl ammonium hydrogen sulphate to give 1-t-butoxycarbonylmethyl-2-chloroimidazole. Reaction of this compound with trimethyloxonium tetrafluoroborate in CH2Cl2 gave 1-t-butoxycarbonylmethyl-2-chloro-3-methylimidazolium tetrafluoroborate; n.m.r. in d6DMSO: 1.5 (s, 9H); 3.9 (s, 3H); 5.17 (s, 2H); 7.81 (d, 1H): 7.85 (d, 1H).