HCID 13910474, compound → N-Benzoyl-5-chloro-2-oxo-2,3-dihydro-1H-indole-1-carboxamide

HRID 2118619Notes

Reaction equation

HRID 2118619 reaction equation
[C:1]([NH:5][C:6]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([Cl:17])=[CH:14][CH:15]=2)[CH2:10][C:9]1=[O:18])=[O:7])(=[O:4])[CH2:2][CH3:3].C(NC(N1C2[C:31](=[CH:32]C(Cl)=CC=2)[CH2:30][C:29]1=O)=O)(=O)C(C)(C)C.C(NC(N1C2C(=CC(F)=CC=2)CC1=O)=O)(=O)CCC.C(NC(N1C2C(=CC(F)=CC=2)CC1=O)=O)(=O)C1C=CC=CC=1.C(NC(N1C2C(=CC(F)=CC=2)CC1=O)=O)(=O)C.C(NC(N1C2C(=CC(Br)=CC=2)CC1=O)=O)(=O)C1C=CC=CC=1.C(NC(N1C2C(=CC(Br)=CC=2)CC1=O)=O)(=O)CC>>[C:1]([NH:5][C:6]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([Cl:17])=[CH:14][CH:15]=2)[CH2:10][C:9]1=[O:18])=[O:7])(=[O:4])[C:2]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:3]=1

Participants

8

Reactant 7

HCID 13910474HCID 13910474, compoundHCID 13910490HCID 13910490, compoundHCID 20194053HCID 20194053, compoundHCID 20194058HCID 20194058, compoundHCID 20194059HCID 20194059, compoundHCID 20194065HCID 20194065, compoundHCID 20194069HCID 20194069, compound

Product 1

HCID 13910470N-Benzoyl-5-chloro-2-oxo-2,3-dihydro-1H-indole-1-carboxamide

Procedure

Using a similar procedure, 1-(N-propionylcarbamoyl)-5-chlorooxindole, 1-(N-pivaloylcarbamoyl)-5-chlorooxindole, 1-(N-butyrylcarbamoyl)-5-fluorooxindole, 1-(N-benzoyl-carbamoyl)-5-fluorooxindole, 1-(N-acetylcarbamoyl)-5-fluorooxindole, 1-(N-benzoylcarbamoyl)-5-bromooxindole, 1-(N-i-butyrylcarbamoyl)-5-bromooxindole and 1-(N-propionylcarbamoyl)-5-bromooxindole are prepared.

Workup

  1. customare prepared

Sources & evidence

ORD record
ord-1d949a815ac64c62a177e8363d94e0ac
Source dataset
uspto-grants-1987_07
Patent number
US04678802

Reaction notes

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