反应详情

6.4 g of phenylcarbamoylmethyl bromide and 3.7 g of selenourea were boiled in 100 ml of acetone under reflux for one four. Then, the mixture was cooled, thereby to form a precipitate. The precipitate was filtered off to obtain phenylcarbamoylmethyl selenoisourea hydrobromide ##STR14## Then, 30 ml of an aqueous solution containing 3.4 g (10 mmol) of the above-obtained phenylcarbamoylmethyl selenoisourea hydrobromide was prepared. To the thus obtained solution was dropwise added 20 ml of an aqueous potassium carbonate solution containing 1.66 g (12 mmol) of potassium carbonate at -10° C. To the obtained solution was dropwise added 3.51 g (10 mmol) of triethylphosphine gold chloride dissolved in ethanol containing a few drops of methylene chloride at -10° C. and then, the mixture was stirred for one hour at -10° C. to precipitate crystals. The crystals were filtered off, washed with water-ethanol and water, successively, and dried. Thus, there was obtained 2.9 g (5.5 mmol) of [(phenylcarbamoyl) methyl]seleno (triethylphosphine) gold.

1. temperatureunder reflux for one four
2. temperatureThen, the mixture was cooled
3. customto form a precipitate
4. filtrationThe precipitate was filtered off