HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatoic Anhydride → 2-Amino-N-[4-(1H-imidazol-1-yl)butyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatoic Anhydride | HCID 8359 | — |
| Reactant | 4-(1H-imidazol-1-yl)butan-1-amine | HCID 4379480 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-N-[4-(1H-imidazol-1-yl)butyl]benzamide | HCID 13952734 | — |
Reaction Steps
A mixture of 1.63 g of isatoic anhydride, 1.39 g of 1H-imidazole-1-butanamine and 25 ml of ethanol was stirred at room temperature for 22 hours. The reaction mixture was concentrated and the residue was dissolved in ethyl acetate and cooled. The desired product was isolated by filtration, mp 91°-93° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04680293 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-b438f73f163d461ea2b374279fe36666 |
| Source note | uspto-grants-1987_07 |