HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloroisatoic anhydride → 2-Amino-5-chloro-N-[3-(1H-imidazol-1-yl)propyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloroisatoic anhydride | HCID 78480 | — |
| Reactant | 1H-Imidazole-1-propanamine | HCID 78736 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-5-chloro-N-[3-(1H-imidazol-1-yl)propyl]benzamide | HCID 13588960 | — |
Reaction Steps
A mixture of 7.92 g of 5-chloroisatoic anhydride, 5.0 g of 1H-imidazole-1-propanamine and 75 ml of ethanol was stirred at room temperature for 20 hours and concentrated. The residue was washed onto a filter with ethanol, then washed with ether to give the desired product, mp 155°-157° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04680293 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-283a6fee03874373a246bff2582079a6 |
| Source note | uspto-grants-1987_07 |