Sodium Hydroxide → HCID 178477873, compound

HRID 2118672Notes

Reaction equation

HRID 2118672 reaction equation
Cl.[C:2]1([NH:8][C:9]([NH:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][C:24]2[C:33]3[C:28](=[CH:29][C:30]([Cl:34])=[CH:31][CH:32]=3)[N:27]=[CH:26][CH:25]=2)=[N:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[Na+]>O>[C:11]1([NH:10][C:9]([NH:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][C:24]2[C:33]3[C:28](=[CH:29][C:30]([Cl:34])=[CH:31][CH:32]=3)[N:27]=[CH:26][CH:25]=2)=[N:8][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178478527HCID 178478527, compound

Product 1

HCID 178477873HCID 178477873, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

10.0 g of 1,2-diphenyl-3-[6-(7-chloro-4-quinolinyl)hexyl]guanidine hydrochloride is dissolved in 500 ml water. An excess of aqueous sodium hydroxide is then added to the solution. The solution is extracted with methylene chloride and the extract is dried and evaporated to afford 1,2-diphenyl-3-[6-(7-chloro-4-quinolinyl)hexyl]guanidine.

Workup

  1. extractionThe solution is extracted with methylene chloride
  2. customthe extract is dried
  3. customevaporated

Sources & evidence

ORD record
ord-72126c40da1947289d7ab2f5e8421188
Source dataset
uspto-grants-1987_07
Patent number
US04680300

Reaction notes

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