Azacyclonol → HCID 13787430, compound

HRID 2118680Notes

Reaction equation

HRID 2118680 reaction equation
[C:1]1([C:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([OH:14])[CH:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:22][CH2:23][CH2:24][N:25]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[C:28](=[O:35])[NH:27][C:26]1=[O:36]>C(O)C>[C:1]1([C:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([OH:14])[CH:8]2[CH2:9][CH2:10][N:11]([CH2:22][CH2:23][CH2:24][N:25]3[C:34]4[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=4)[C:28](=[O:35])[NH:27][C:26]3=[O:36])[CH2:12][CH2:13]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 15723AzacyclonolHCID 134765441-(3-Chloropropyl)quinazoline-2,4(1H,3H)-dione

Product 1

HCID 13787430HCID 13787430, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.7 g (0.01 mole) of 4-(diphenylhydroxymethyl) piperidine, 1.2 g (0.005 mole) of 1-(3-chloropropyl)-2,4(1H,3H)-quinazolinedione in 75 ml of ethanol are heated at reflux temperature for 7 h.

Workup

  1. temperatureat reflux temperature for 7 h.

Sources & evidence

ORD record
ord-b90e8d0acc33487baf767087de96bc27
Source dataset
uspto-grants-1987_07
Patent number
US04680296

Reaction notes

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