Oleoyl chloride → HCID 86741672, compound

HRID 2118705Notes

Reaction equation

HRID 2118705 reaction equation
[CH2:1]([NH:19][CH:20]1[O:28][C@@H:27]([CH3:29])[C@@H:25]([OH:26])[C@@H:23]([OH:24])[C@@H:21]1[OH:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[C:30](Cl)(=[O:48])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]/[CH:38]=[CH:39]\[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47]>C(Cl)Cl.CO>[CH:20]1([N:19]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[C:30](=[O:48])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]/[CH:38]=[CH:39]\[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])[O:28][C@@H:27]([CH3:29])[C@@H:25]([OH:26])[C@@H:23]([OH:24])[C@@H:21]1[OH:22]

Participants

4

Reactant 2

HCID 5364783Oleoyl chlorideHCID 18608592HCID 18608592, compound

Product 1

HCID 86741672HCID 86741672, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

2.9 g of the compound from Example 22 are acylated with oleoyl chloride as described in Example 6. Column chromatography with the eluting agent CH2Cl2 /CH3OH=15/1.

Sources & evidence

ORD record
ord-fd280b82b3554f8c843cf18e8c954e22
Source dataset
uspto-grants-1987_07
Patent number
US04680287

Reaction notes

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