Water → 2-Tert-butyl-5-chloro-6-nitrobenzothiazole

Participants

Reaction Steps

A mixture of 94 g of N-tert-butylthiocarbonyl-2,5-dichloro-4-nitroaniline, described in Example 1, in 360 ml of dimethylsulphoxide and 160 ml of triethylamine is heated at 140° for 10 hours under nitrogen. The reaction mixture is cooled and poured into water. The solid obtained is filtered and washed with water and air-dried to yield 2-tert-butyl-5-chloro-6-nitrobenzothiazole, melting at 65°-69°.

Provenance & Evidence