Water → HCID 20192943, compound

Participants

Reaction Steps

A solution of 2.7 g of 2-tert-butyl-5-chloro-6-nitrobenzothiazole described in example 5, in 25 ml of dimethyl sulfoxide is stirred and heated at 140° for 11 hours with 2.6 g of anhydrous potassium carbonate and 1 g of 3-methylpiperidine, cooled and poured into water. The material obtained is dissolved in chloroform and filtered through a silica gel column. The filtrate is evaporated to give 2-tert-butyl-5-[3-methylpiperidin-1-yl]-6-nitrobenzothiazole as an oil.

Provenance & Evidence