HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzoic Acid → 4-Isothiocyanatobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzoic Acid | HCID 978 | — |
| Reactant | Thiophosgene | HCID 10040 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-Isothiocyanatobenzoic acid | HCID 242946 | — |
Reaction Steps
A sample of p-aminobenzoic acid is dissolved in 3N HCl (20% by weight). To this is added about one equivalent of thiophosgene in a single portion. The reaction mixture is stirred until a white precipitate appears, the crude product is filtered, washed with water, and crystallized from acetone-water to give crude p-isothiocyanatobenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04680338 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-02356b00b69a405d95134e8cab1c4d4a |
| Source note | uspto-grants-1987_07 |