HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → (S)-Benzyl (tetrahydro-2,5-dioxo-3-furyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | N-(Benzyloxycarbonyl)aspartic acid | HCID 2723942 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (S)-Benzyl (tetrahydro-2,5-dioxo-3-furyl)carbamate | HCID 11128682 | 75% |
Reaction Steps
To a suspension of 16.0 g N-benzyloxycarbonyl-L-aspartic acid (Z-Asp) in 24 ml toluene, was added 7.7 g of acetic anhydride, and the reaction was continued at room temperature for six hours to form N-benzyloxycarbonyl-L-aspartic anhydride (Z-Asp O).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04680403 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-64df422fbe084e798452d5bdbd16193f |
| Source note | uspto-grants-1987_07 |