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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2118809Generated: October 25, 2026

Piperidine → [2-(1-Piperidinyl)-3-nitrophenyl]-(4-chlorophenyl)-methanone

https://huagongshe.com/reaction/2118809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
ReactantCalcium CarbonateHCID 10112—
Reactant(2-Chloro-5-nitro-phenyl)-(4-chloro-phenyl)-methanoneHCID 875720—
SolventEthanolHCID 702—
Product[2-(1-Piperidinyl)-3-nitrophenyl]-(4-chlorophenyl)-methanoneHCID 2019352397%

Reaction Steps

Proceeding as in example 2, with 0.035 mole (10.4 g) of 2,4'-dichloro-5-nitro-benzophenone and 0.07 mole (6 g) of piperidine and 0.035 mole (5 g) of calcium carbonate mixed in ethanol, 11 g (Yield: 97%) of the expected product are obtained after recrystallization in ethanol. M.P.=141° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04680402
Source datasetuspto-grants-1987_07
ORD IDord-7d7d8dbd960c416c972f83faf07a8d90
Source noteuspto-grants-1987_07