HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyrimidine → HCID 23035484, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | 3-(3-(Piperidin-1-ylmethyl)phenoxy)propan-1-amine | HCID 10220561 | — |
| Product | HCID 23035484 | HCID 23035484 | — |
Reaction Steps
3-[3-(Piperidinomethyl)phenoxy]propylamine (2.0 g) and 2-chloropyrimidine (0.92 g) were fused at 160° C. for one hour. The reaction mixture was worked-up in a manner similar to that of Example 3 to give the title compound as an oil. This was treated with oxalic acid to give 2-[3-[3-(piperidinomethyl)phenoxy]propylamino]pyrimidine dioxalate (0.8 g), m.p. 181°-183° C. (recrystallised from methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04681883 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-a7ddcf5ef6c3420ead0f81634d14066a |
| Source note | uspto-grants-1987_07 |