HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 23035470, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Propanoic acid, 3-(3-(1-piperidinylmethyl)phenoxy)- | HCID 154971 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 23035470 | HCID 23035470 | — |
Reaction Steps
Thionyl chloride (23.8 g) was added slowly to a cooled (0° C.) mixture of 3-[3-(piperidinomethyl)phenoxy]propionic acid and dimethylformamide (0.5 ml) in dichloromethane (100 ml). The resulting suspension was stirred at room temperature overnight, and solvent was removed under reduced pressure to give 3-[3-(piperidinomethyl)phenoxy]propionyl chloride hydrochloride (18.9 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04681883 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-1b7ae4cf623f44cf98d2b6551372d29a |
| Source note | uspto-grants-1987_07 |