3'-Azido-2',3'-dideoxy-5-ethyluridine → Uridine, 3'-amino-2',3'-dideoxy-5-ethyl-

Participants

Reaction Steps

An aqueous solution (15 ml) of 3'-azido-5-ethyl-2',3'-dideoxyuridine (376 mg) is hydrogenated with 10% Pd/C (100 mg) at room temperature under 1 atmosphere for one hour. The mixture is filtered through a celite pad, evaporated down to ca. 2 ml, and then freeze-dried to obtain a foam (300 mg, 88%).

Provenance & Evidence