反应详情

A mixture of 20 g (111 millimoles) of sorbose, 2 ml (16.4 millimoles) of boron trifluoride etherate and 400 ml of acetone was refluxed for 4 hours, the condensate flowing back being dried as described in Example 1. When 0.4 g (10.5 millimoles) of sodium methylate were added and the mixture worked up as described in Example 5, 23.5 g (81%) of 2,3:4,6-di-O-isopropylidene-α-L-sorbofuranose were obtained.

1. temperaturewas refluxed for 4 hours
2. customthe condensate flowing back being dried