2-Pyridone → 2-Pyridone

HRID 2119046Notes

Reaction equation

HRID 2119046 reaction equation
[Cl:1][C:2]1[C:3](=[O:9])[NH:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[NH:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]1=[O:16]>>[Cl:1][C:2]1[C:3](=[O:9])[NH:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[Cl:8][C:6]1[CH:7]=[CH:2][C:3](=[O:9])[NH:4][CH:5]=1.[NH:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]1=[O:16]

Participants

5

Reactant 2

HCID 88712-PyridoneHCID 794963,5-Dichloro-2-pyridone

Product 3

HCID 88712-PyridoneHCID 778895-Chloro-2-pyridinolHCID 794963,5-Dichloro-2-pyridone

Procedure

The production of 3,5-dichloro-2-pyridone in a yield of 63 percent by chlorination, starting from 2-pyridone is known [Cava et al., J. Org. Chem. 23, 1614 (1958)]. According to U.S.S.R. Pat. No 194,823 (Appl. 4/20/1966), it is also known to obtain 3,5-dichloro-2-pyridone in mixture with 5-chloropyridone starting from 2-pyridone by reaction with tert-butyl hypochlorite.

Sources & evidence

ORD record
ord-99f28d01dd1943ccba3e7ce2b9a732c7
Source dataset
uspto-grants-1987_07
Patent number
US04681942

Reaction notes

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