HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 70401492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 6-Chloropurine riboside | HCID 93003 | — |
| Reactant | HCID 20190905 | HCID 20190905 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 70401492 | HCID 70401492 | 50% |
Reaction Steps
A mixture of 2.25 g of 6-chloropurine riboside, 1.99 g of 8-chloro-3-chromanylamine hydrochloride, and 1.98 g triethylamine is refluxed in 55 ml of ethanol under nitrogen for 22 hrs. Upon cooling, solid material crystallizes out, which is filtered and retreated with boiling ethanol. Solid material obtained is filtered and dried affording 1.68 g (50%) of N6 -[8-chloro-3-chromanylamino]adenosine having a melting point of 137°-139° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04683223 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-5579c6fdcbb24985a13d85f65e65a0d3 |
| Source note | uspto-grants-1987_07 |