Triethylamine → HCID 13644556, compound

Participants

Reaction Steps

1.00 g (3.30 millimole) of 5-Ethoxycarbonyl-2.6-dimethyl-4-(2-nitrophenyl)-dihydropyrimidine was dissolved in 15 ml of chloroform. To the solution, 2 ml of triethylamine (14.3 millimole) was added with stirring and then 0.4 g (4.32 millimole) of propionyl chloride was added dropwise. The mixture was stirred at room temperature for 40 minutes and concentrated under reduced pressure. The residue was purified on silica gel by column chromatography and recrystallized from benzene/hexane to obtain 0.69 g (58% yield) of title compound.

Provenance & Evidence