5-(Chloromethyl)-2-methylpyridine → HCID 11732192, compound

HRID 2119317Notes

Reaction equation

HRID 2119317 reaction equation
[Cl:1][CH2:2][C:3]1[CH:4]=[CH:5][C:6]([CH3:9])=[N:7][CH:8]=1.[Cl-].[C:11]1([P+:17]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)CC2C=NC=CC=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[Cl-:1].[C:31]1([P+:17]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:2][C:3]2[CH:8]=[N:7][C:6]([CH3:9])=[CH:5][CH:4]=2)[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1

Participants

3

Reactant 2

HCID 122143385-(Chloromethyl)-2-methylpyridineHCID 22325077Triphenyl(3-pyridylmethyl)phosphonium chloride

Product 1

HCID 11732192HCID 11732192, compound

Procedure

Prepared from 5-chlormethyl-2-methyl-pyridine (Arch. Pharm. 1975, 308, 359) as described in expl. 1a): 1H-NMR (DMSO-d6) inter alia 5.24 (d, J=15.6 Hz, H2C), 2.38 (s H3C).

Sources & evidence

ORD record
ord-69d6fad2da944489bec8f389f558173f
Source dataset
uspto-grants-2004_02
Patent number
US06686347B2

Reaction notes

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