HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2119331Generated: October 29, 2026
4-Chlorobenzylamine → HCID 178482192, compound
https://huagongshe.com/reaction/2119331
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chlorobenzylamine | HCID 66036 | — |
| Reactant | HCID 178469660 | HCID 178469660 | — |
| Product | HCID 178482192 | HCID 178482192 | — |
Reaction Steps
A mixture of ethyl 4-hydroxy-8-(methylamino)-6-(4-morpholinylmethyl)-3-quinolinecarboxylate (280 mg) and 4-chlorobenzylamine (1.5 mL) is heated under nitrogen at 200° C. for 30 min. The bulk of the 4-chlorobenzylamine is removed under reduced pressure, and the product is purified by chromatography on silica gel to give 169 mg of the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06686356B2 |
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| Source dataset | uspto-grants-2004_02 |
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| ORD ID | ord-94219c6fef394932af79b857a1e922d1 |
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| Source note | uspto-grants-2004_02 |
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