HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Malonate → 2-(2,6-difluoro-4-nitrophenyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Malonate | HCID 7761 | — |
| Reactant | 1,2,3-Trifluoro-5-nitrobenzene | HCID 2782793 | — |
| Product | 2-(2,6-difluoro-4-nitrophenyl)acetic acid | HCID 69837344 | — |
Reaction Steps
The title compound 2,6-difluoro-4-nitrophenylacetic acid (16.0 g) was prepared from 3,4,5-trifluoronitrobenzene (14.8 g) and diethyl malonate (35 mL) in the same manner as described for REFERENCE EXAMPLE 1. MS (EI+) m/z: 217 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06686363B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-57372b96301846fb8b0bc7137b15eefc |
| Source note | uspto-grants-2004_02 |