1-Bromo-3,5-difluorobenzene → 3-(3,5-Difluoro-phenylamino)-6-methyl-pyridine-2-carboxylic acid (4-cyclopropyl-thiazol-2-yl)-amide
Reaction equation
[Br:20][c:21]1[cH:22][c:23]([F:28])[cH:24][c:25]([F:27])[cH:26]1.[CH:1]1([c:4]2[n:5][c:6]([NH:9][C:10](=[O:11])[c:12]3[n:13][c:14]([CH3:19])[cH:15][cH:16][c:17]3[NH2:18])[s:7][cH:8]2)[CH2:2][CH2:3]1>>[CH:1]1([c:4]2[n:5][c:6]([NH:9][C:10](=[O:11])[c:12]3[n:13][c:14]([CH3:19])[cH:15][cH:16][c:17]3[NH:18][c:21]3[cH:22][c:23]([F:28])[cH:24][c:25]([F:27])[cH:26]3)[s:7][cH:8]2)[CH2:2][CH2:3]1Participants
3
Sources & evidence
- ORD record
- ord-f609f5f36c3249b0bf82fb96b78ec2aa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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