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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 211945Generated: October 25, 2026

1-Fluoro-4-(methylsulphonyl)benzene → 2-Hydroxymethyl-4-(4-methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/211945

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-4-(methylsulphonyl)benzeneHCID 67994—
Reactant4-Hydroxy-2-hydroxymethyl-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl esterHCID 59559905—
Reactant6-(4-Methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-4-carboxylic acid methyl esterHCID 59560437—
Product2-Hydroxymethyl-4-(4-methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl esterHCID 59559858—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-40afd6de23644fbf8b625937cfbaeccf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)