HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethoxybenzoyl chloride → 1-(2,6-Dimethoxylbenzoyl)-3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-5-azaindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethoxybenzoyl chloride | HCID 74810 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | 3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-1H-5-Azaindole | HCID 10130974 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(2,6-Dimethoxylbenzoyl)-3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-5-azaindole | HCID 9801306 | — |
Reaction Steps
from 3-(1,2,3,5,8,8a-hexahydro-7-indolizinyl)-1H-5-Azaindole (10 mg, 0.0418 mmol), 2,6-dimethoxylbenzoyl chloride (20 mg, 0.0997 mmol) and 1M NaN(TMS)2 (100 μL, 0.10 mmol) in THF (1 mL) at RT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06686374B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-b92b60e39d634367b1cd0f947354053f |
| Source note | uspto-grants-2004_02 |