HCID 23442274, compound → HCID 23442263, compound

HRID 2119668Notes

Reaction equation

HRID 2119668 reaction equation
C[O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:7]3[C:8]([C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([O:28]CC5C=CC=CC=5)[CH:23]=4)=[C:9]4[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:10]4=[CH:11][C:12]=3[CH2:13][C:14]=2[CH:15]=1.C(OC1C=C([Li])C=CC=1)C1C=CC=CC=1>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]2[C:7]3[C:8]([C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([OH:28])[CH:23]=4)=[C:9]4[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:10]4=[CH:11][C:12]=3[CH2:13][C:14]=2[CH:15]=1

Participants

3

Reactant 2

HCID 23442274HCID 23442274, compoundHCID 178506723HCID 178506723, compound

Product 1

HCID 23442263HCID 23442263, compoundYield 14%

Procedure

Compound 62b was prepared from 2,8-dimethoxy-5-(3-benzyloxyphenyl)-11H-benzo[b]fluorene, 61b, in 14% yield, in the same fashion as described for the preparation of 62a, but using 3-(benzyloxy) phenyl lithium instead of 4-(benzyloxy) phenyl lithium (Rf<0.26 CH2Cl2/methanol (9:1)); ESI-MS: M+H=341.2, M−H=339.0.

Sources & evidence

ORD record
ord-61c8c0fd3ec443b98279daa977ee7f28
Source dataset
uspto-grants-2004_02
Patent number
US06686371B2

Reaction notes

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