HCID 86586188, compound → HCID 12094377, compound

Participants

Reaction Steps

0.51 g of 6-t-butyl-5-hydroxy-4-(2-propenyl)-2,3-dihydrobenzofuran-2-spiro-1′-cycloheptane synthesized in Example 8 was dissolved in 5 ml of ethanol and the solution was vigorously stirred with 0.05 g of 10% palladium on carbon overnight under a hydrogen stream. After the palladium on carbon was filtered off, the mixture was concentrated and the concentrate was purified by silica gel column chromatography (in n-hexane containing 1% ethyl acetate) to give 0.49 g of 6-t-butyl-5-hydroxy-4-n-propyl-2,3-dihydrobenzofuran-2-spiro-1′-cycloheptane as a white solid (yield 95%).

Provenance & Evidence