HCID 23442860, compound → HCID 23442859, compound

HRID 2119733Notes

Reaction equation

HRID 2119733 reaction equation
C([O:4][C:5]1[C:6]([C:17]([CH3:20])([CH3:19])[CH3:18])=[CH:7][C:8]([OH:16])=[C:9]([C:12]=1[CH:13]([CH3:15])[CH3:14])[CH:10]=O)(=O)C.C([O:24][C:25]1[C:26]([CH:38]([CH3:40])[CH3:39])=[CH:27][C:28]([OH:37])=[C:29]([C:32]=1[C:33]([CH3:36])([CH3:35])[CH3:34])[CH:30]=O)(=O)C>>[C:17]([C:6]1[C:5]([OH:4])=[C:12]([CH:13]([CH3:14])[CH3:15])[C:9]2[CH2:10][C:25]([CH3:26])([CH3:32])[O:16][C:8]=2[CH:7]=1)([CH3:18])([CH3:19])[CH3:20].[C:33]([C:32]1[C:29]2[CH2:30][C:5]([CH3:6])([CH3:12])[O:37][C:28]=2[CH:27]=[C:26]([CH:38]([CH3:40])[CH3:39])[C:25]=1[OH:24])([CH3:34])([CH3:35])[CH3:36]

Participants

4

Reactant 2

HCID 23442860HCID 23442860, compoundHCID 23442869HCID 23442869, compound

Product 2

HCID 23442859HCID 23442859, compoundHCID 23442861HCID 23442861, compound

Procedure

The mixture of 5-acetoxy-4-t-butyl-2-hydroxy-6-isopropylbenzaldehyde and 5-acetoxy-6-t-butyl-2-hydroxy-4-isopropylbenzaldehyde was treated in the same manner as in Examples 19-4), 5) and 6) to give 171 mg of 6-t-butyl-5-hydroxy-2,2-dimethyl-4-isopropyl-2,3-dihydrobenzofuran as a white solid and 75 mg of 4-t-butyl-5-hydroxy-2,2-dimethyl-6-isopropyl-2,3-dihydrobenzofuran as a white solid.

Workup

  1. additionwas treated in the same manner as in Examples 19-4), 5) and 6)

Sources & evidence

ORD record
ord-d114f81831ce40ac989a8d1abb96a17f
Source dataset
uspto-grants-2004_02
Patent number
US06686389B2

Reaction notes

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