4-Fluorobenzaldehyde → HCID 9992879, compound
Reaction equation
[CH3:1][N:2]([CH2:8][CH2:9][OH:10])[C:3]1[S:4][CH:5]=[CH:6][N:7]=1.F[C:12]1[CH:19]=[CH:18][C:15]([CH:16]=[O:17])=[CH:14][CH:13]=1>>[CH3:1][N:2]([CH2:8][CH2:9][O:10][C:12]1[CH:19]=[CH:18][C:15]([CH:16]=[O:17])=[CH:14][CH:13]=1)[C:3]1[S:4][CH:5]=[CH:6][N:7]=1Participants
3
Procedure
The title compound was prepared from 2-[N-methyl-N-(2-thiazolyl)amino]ethanol (10.7 g) and 4-fluorobenzaldehyde (15.9 g) by an analogous procedure to that described in Preparation 5.
Workup
- customthat described in Preparation 5
Sources & evidence
- ORD record
- ord-932f45a3379e48ecbd3e9d375c440c61
- Source dataset
- uspto-grants-2004_02
- Patent number
- US06686475B2
Reaction notes
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