HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1H-indol-3-yl)ethanimidamide → 5,7-Dihydro-2-[1H-indol-3-yl-methyl]9,10-dimethyl-6H-pyrimido[5,4-d]benzazepine-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1H-indol-3-yl)ethanimidamide | HCID 4046639 | — |
| Reactant | 4-[(Dimethylamino)methylene]-3,4-dihydro-7,8-dimethyl-1h-benzazepine-2,5-dione | HCID 69923555 | — |
| Product | 5,7-Dihydro-2-[1H-indol-3-yl-methyl]9,10-dimethyl-6H-pyrimido[5,4-d]benzazepine-6-one | HCID 23440958 | 72% |
Reaction Steps
Analogous to Scheme 1, from 4-[(dimethylamino)methylene]-3,4-dihydro-7,8-dimethyl-1H-benzazepine-2,5-dione and 2-(1H-indol-3-yl)-acetamidine. Yield: 72%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06686352B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-66bf274a7a074d549043d8dd90c3c3d5 |
| Source note | uspto-grants-2004_02 |