Water → Benzene, 1-bromo-4-(hexyloxy)-

Participants

Reaction Steps

In 200 g of ethanol were dissolved 86.5 g (0.5 mol) of 4-bromophenol and 22 g (0.55 mol) of sodium hydroxide. To the solution at 70° C., 90.8 g (0.55 mol) of n-hexyl bromide was added dropwise. The solution was allowed to ripen for 4 hours and cooled to room temperature, after which 120 g of water was added. The oily matter was separated therefrom and concentrated by a rotary evaporator, followed by vacuum distillation (boiling point 125-128° C./0.5 Torr), yielding 100 g of 4-n-hexyloxyphenyl bromide.

Provenance & Evidence