Ethylenediamine → HCID 135597354, compound

HRID 2120052Notes

Reaction equation

HRID 2120052 reaction equation
[CH2:1]([NH2:4])[CH2:2][NH2:3].[CH2:5]([N:7]([C:9]1[CH:10]=[C:11]([OH:17])[C:12](=[CH:15][CH:16]=1)[CH:13]=O)[CH3:8])[CH3:6]>>[CH2:5]([N:7]([C:9]1[CH:10]=[C:11]([OH:17])[C:12](=[CH:15][CH:16]=1)[CH:13]=[N:3][CH2:2][CH2:1][N:4]=[CH:13][C:12]1[C:11](=[CH:10][C:9]([N:7]([CH3:8])[CH2:5][CH3:6])=[CH:16][CH:15]=1)[OH:17])[CH3:8])[CH3:6]

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 22664951HCID 22664951, compound

Product 1

HCID 135597354HCID 135597354, compound

Conditions

Temperature
70 °C

Procedure

A solution of 80 mg (1.33 mmol) of ethylenediamine is added dropwise, at room temperature, to a solution of 500 mg (2.79 mmol) of 4-(N-ethyl-N-methylamino)salicylaldehyde and the reaction solution is heated for 4 hours at 70° C. After cooling to room temperature, the precipitate formed is filtered off, washed with a small amount of cold ethanol and dried in a vacuum drying cabinet at 30° C.

Workup

  1. temperatureAfter cooling to room temperature
  2. customthe precipitate formed
  3. filtrationis filtered off
  4. washwashed with a small amount of cold ethanol
  5. customdried in a vacuum
  6. customdrying cabinet at 30° C.

Sources & evidence

ORD record
ord-4a10ff10e5cd44669b1735381efe7260
Source dataset
uspto-grants-2004_02
Patent number
US06689733B1

Reaction notes

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