1,2-Diaminocyclohexane, trans- → HCID 136372444, compound

HRID 2120054Notes

Reaction equation

HRID 2120054 reaction equation
[CH:1]([N:4]([C:6]1[CH:7]=[C:8]([OH:14])[C:9](=[CH:12][CH:13]=1)[CH:10]=O)[CH3:5])([CH3:3])[CH3:2].[C@@H:15]1([NH2:22])[CH2:20][CH2:19][CH2:18][CH2:17][C@H:16]1[NH2:21]>>[CH:1]([N:4]([C:6]1[CH:7]=[C:8]([OH:14])[C:9](=[CH:12][CH:13]=1)[CH:10]=[N:21][C@@H:16]1[CH2:17][CH2:18][CH2:19][CH2:20][C@H:15]1[N:22]=[CH:10][C:9]1[C:8](=[CH:7][C:6]([N:4]([CH3:5])[CH:1]([CH3:2])[CH3:3])=[CH:13][CH:12]=1)[OH:14])[CH3:5])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 438061,2-Diaminocyclohexane, trans-HCID 22664949HCID 22664949, compound

Product 1

HCID 136372444HCID 136372444, compound

Procedure

Synthesis and working up are carried out as in Example 9, starting from 500 mg (2.59 mmol) of 4-(N-isopropyl-N-methylamino)salicylaldehyde and 141 mg (1.23 mmol) of trans-1,2-cyclohexanediamine. Yield: 504 mg (88%), yellow solid.

Workup

  1. customSynthesis

Sources & evidence

ORD record
ord-b6b80b0a7b2e429a878fb42a47740309
Source dataset
uspto-grants-2004_02
Patent number
US06689733B1

Reaction notes

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