1,2-Diaminocyclohexane, trans- → HCID 136388366, compound

HRID 2120055Notes

Reaction equation

HRID 2120055 reaction equation
[CH2:1]([N:3]([C:5]1[CH:6]=[C:7]([OH:13])[C:8](=[CH:11][CH:12]=1)[CH:9]=O)[CH3:4])[CH3:2].[C@@H:14]1([NH2:21])[CH2:19][CH2:18][CH2:17][CH2:16][C@H:15]1[NH2:20]>>[CH2:1]([N:3]([C:5]1[CH:6]=[C:7]([OH:13])[C:8](=[CH:11][CH:12]=1)[CH:9]=[N:20][C@@H:15]1[CH2:16][CH2:17][CH2:18][CH2:19][C@H:14]1[N:21]=[CH:9][C:8]1[C:7](=[CH:6][C:5]([N:3]([CH3:4])[CH2:1][CH3:2])=[CH:12][CH:11]=1)[OH:13])[CH3:4])[CH3:2]

Participants

3

Reactant 2

HCID 438061,2-Diaminocyclohexane, trans-HCID 22664951HCID 22664951, compound

Product 1

HCID 136388366HCID 136388366, compound

Procedure

Synthesis and working up are carried out as in Example 9, starting from 500 mg (2.79 mmol) of 4-(N-ethyl-N-methylamino)salicylaldehyde and 152 mg (1.33 mmol) of trans-1,2-cyclohexanediamine. Yield: 569 mg (98%), yellow solid.

Workup

  1. customSynthesis

Sources & evidence

ORD record
ord-908bcd9dad83499a878583cf4a08d6bb
Source dataset
uspto-grants-2004_02
Patent number
US06689733B1

Reaction notes

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