Methanol → HCID 135587754, compound

HRID 2120058Notes

Reaction equation

HRID 2120058 reaction equation
[CH3:1][OH:2].[N+:3]([C:6]1[CH:7]=[C:8]([OH:14])[C:9](=[CH:12][CH:13]=1)[CH:10]=O)([O-:5])=[O:4].[CH2:15]([NH2:18])[CH2:16][NH2:17]>C(O)C>[N+:3]([C:6]1[CH:7]=[C:8]([OH:14])[C:9](=[CH:12][CH:13]=1)[CH:10]=[N:17][CH2:16][CH2:15][N:18]=[CH:8][C:9]1[C:1](=[CH:7][C:6]([N+:3]([O-:5])=[O:4])=[CH:13][CH:12]=1)[OH:2])([O-:5])=[O:4]

Participants

5

Reactant 3

HCID 887MethanolHCID 3301EthylenediamineHCID 755702-Hydroxy-4-nitrobenzaldehyde

Product 1

HCID 135587754HCID 135587754, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
70 °C

Procedure

4 ml of methanol are added to a solution of 500 mg (2.99 mmol) of 4-nitrosalicylaldehyde (for preparation see Beilstein E IV, Vol. 8, 232) in 2 ml of ethanol. 95.2 mg (106 μl, 1.58 mmol) of ethylenediamine are added dropwise to the resulting yellow suspension. The reaction suspension is heated for 4 hours at 70° C. After cooling to room temperature, the precipitate formed is filtered off, washed with 2 ml of ethanol and dried to constant weight under a high vacuum at 30° C.

Workup

  1. temperatureAfter cooling to room temperature
  2. customthe precipitate formed
  3. filtrationis filtered off
  4. washwashed with 2 ml of ethanol
  5. customdried to constant weight under a high vacuum at 30° C.

Sources & evidence

ORD record
ord-1ab742eff1d44ca7ba3145aef4d0a0c1
Source dataset
uspto-grants-2004_02
Patent number
US06689733B1

Reaction notes

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