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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120139Generated: October 25, 2026

4-(oxiran-2-ylmethoxy)-1H-indole → 1-(1H-Indol-4-yloxy)-3-[4-(1H-benzimidazole-4-yl) piperazin-1-yl]-propan-2-ol

https://huagongshe.com/reaction/2120139

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(oxiran-2-ylmethoxy)-1H-indoleHCID 605015—
Reactant1-(1H-benzimidazol-4-yl)piperazineHCID 3069490—
Product1-(1H-Indol-4-yloxy)-3-[4-(1H-benzimidazole-4-yl) piperazin-1-yl]-propan-2-olHCID 9821835—

Reaction Steps

The title compound is prepared from the reaction of 1-(indole-4-oxy)-2,3-epoxypropane (2.0 mmole) and 1-(1H-benzimidazole-4-yl)piperazine (2 mmole) according to the above procedures.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06689792B2
Source datasetuspto-grants-2004_02
ORD IDord-af2a87630a76439fb0042ad8f4483bf7
Source noteuspto-grants-2004_02