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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120143Generated: November 1, 2026

(2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid → Ethyl (2S,3S)-3-[[1-(S)-[alpha-(R)-methoxybenzyl]-3-methyl-butyl]carbamoyl]oxirane-2-carboxylate

https://huagongshe.com/reaction/2120143

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acidHCID 11030109—
Reactant1-(S)-[alpha-(R)-methoxybenzyl]-3-methylbutylamineHCID 12051472—
ProductEthyl (2S,3S)-3-[[1-(S)-[alpha-(R)-methoxybenzyl]-3-methyl-butyl]carbamoyl]oxirane-2-carboxylateHCID 12051473—

Reaction Steps

The procedures of Example 1a were repeated employing (2S,3S)-3-ethoxycarbonyloxirane-2-carboxylic acid and 1-(S)-[α-(R)-methoxybenzyl]-3-methylbutylamine (its preparation is described in the after-mentioned Reference Example 2) to prepare the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06689785B2
Source datasetuspto-grants-2004_02
ORD IDord-bc4b10d6a4c84faab340405b88d11400
Source noteuspto-grants-2004_02