反应详情

To a solution of 4.1 g (20.0 mmol) of compound obtained in Example 4 in 4 ml of acetone and 96 ml of anhydrous ethanol there is added 10% Pd—C catalyst. The mixture is hydrogenated under a hydrogen pressure of 3-3.5 kg/cm2. After the absorption of hydrogen is complete, the catalyst is filtered off and the filtrate is concentrated in vacuo to dryness. The residue is crystallised from dilute ethanol to give the title compound.

1. customAfter the absorption of hydrogen
2. filtrationthe catalyst is filtered off
3. concentrationthe filtrate is concentrated in vacuo to dryness
4. customThe residue is crystallised from dilute ethanol