HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Pyridin-3-yl-1,3-dihydro-indol-2-one → HCID 53880957, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Pyridin-3-yl-1,3-dihydro-indol-2-one | HCID 21915579 | — |
| Reactant | 4-(3-dimethylaminopropyl)-3,5-dimethyl-1H-pyrrole-2-carbaldehyde | HCID 21925758 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 53880957 | HCID 53880957 | — |
Reaction Steps
A mixture of 6-pyridin-3-yl-1,3-dihydroindol-2-one (100 mg, 0.48 mmol), 4-(3-dimethylaminopropyl)-3,5-dimethyl-1H-pyrrole-2-carboxaldehyde (100 mg, 0.48 mmol), and piperidine (1 drop) in ethanol (2 mL) was stirred at reflux overnight. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 3-[4-(3-dimethylaminopropyl)-3,5-dimethyl-1H-pyrrol-2-ylmethylene]-6-pyridin-3-yl-1,3-dihydroindol-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689806B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-adef299b508d4e08a9679da09665d6af |
| Source note | uspto-grants-2004_02 |