HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-fluoro-1,3-dihydro-2H-indol-2-one → 3-(3-Cyclopentyl-4-methoxybenzylidene)-5-fluoro-1,3-dihydroindol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-fluoro-1,3-dihydro-2H-indol-2-one | HCID 3731012 | — |
| Reactant | 3-Cyclopentyl-4-methoxybenzaldehyde | HCID 22571071 | — |
| Product | 3-(3-Cyclopentyl-4-methoxybenzylidene)-5-fluoro-1,3-dihydroindol-2-one | HCID 53825519 | — |
Reaction Steps
5-Fluoro-2-oxindole was condensed with 3-cyclopentyl-4-methoxybenzaldehyde using method B to give 3-(3-cyclopentyl-4-methoxybenzylidene)-5-fluoro-1,3-dihydro-indol-2-one as a yellow-orange solid, followed by reduction using method E to give 0.78 g (78%) of 3-(3-cyclopentyl-4-methoxybenzyl)-5-fluoro-1,3-dihydroindol-2-one as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689806B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-03aa090ff3074936993d3ffb146890cd |
| Source note | uspto-grants-2004_02 |