Oxindole → HCID 53996334, compound

HRID 2120215Notes

Reaction equation

HRID 2120215 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10].[NH:11]1[C:19]2[C:14](=[CH:15][C:16]([CH:20]=O)=[CH:17][CH:18]=2)[CH:13]=[CH:12]1>>[NH:11]1[C:19]2[C:14](=[CH:15][C:16]([CH:20]=[C:3]3[C:4]4[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=4)[NH:1][C:2]3=[O:10])=[CH:17][CH:18]=2)[CH:13]=[CH:12]1

Participants

3

Reactant 2

HCID 321710OxindoleHCID 589040Indole-5-carboxaldehyde

Product 1

HCID 53996334HCID 53996334, compoundYield 60%

Procedure

2-Oxindole (133 mg, 1 mmol) was condensed with 1H-indole-5-carbaldehyde (145 mg, 1 mmol) using method B to give 155 mg (60%) of 3-(1H-indol-5-ylmethylene)-1,3-dihydroindol-2-one as a white solid.

Sources & evidence

ORD record
ord-dc5e43ae9edf4828b67cde3b66a3fce1
Source dataset
uspto-grants-2004_02
Patent number
US06689806B1

Reaction notes

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