5-Bromosalicylaldehyde → HCID 54106390, compound

HRID 2120224Notes

Reaction equation

HRID 2120224 reaction equation
[C:1]1([C:7]2[CH:15]=[C:14]3[C:10]([CH2:11][C:12](=[O:16])[NH:13]3)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:17][C:18]1[CH:25]=[C:22]([CH:23]=O)[C:21]([OH:26])=[CH:20][CH:19]=1>>[Br:17][C:18]1[CH:19]=[CH:20][C:21]([OH:26])=[C:22]([CH:25]=1)[CH:23]=[C:11]1[C:10]2[C:14](=[CH:15][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:8][CH:9]=2)[NH:13][C:12]1=[O:16]

Participants

3

Reactant 2

HCID 728635-BromosalicylaldehydeHCID 105363846-Phenyl-1,3-dihydro-indol-2-one

Product 1

HCID 54106390HCID 54106390, compoundYield 82%

Procedure

6-Phenyl-2-oxindole (50 mg, 0.3 mmol) was condensed with 5-bromosalicylaldehyde (50 mg, 0.25 mmol) using method B to give 80 mg (82%) of 3-(5-bromo-2-hydroxybenzylidene)-6-phenyl-1,3-dihydroindol-2-one as a yellow/orange solid.

Sources & evidence

ORD record
ord-83c2d1f9d3484bd88423b95fb05489c7
Source dataset
uspto-grants-2004_02
Patent number
US06689806B1

Reaction notes

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