HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chlorooxindole → 3-(3-Bromo-5-tert-butyl-4-hydroxybenzylidene)-5-chloro-1,3-dihydroindol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chlorooxindole | HCID 152801 | — |
| Reactant | 3-Bromo-5-tert-butyl-4-hydroxybenzaldehyde | HCID 14839297 | — |
| Product | 3-(3-Bromo-5-tert-butyl-4-hydroxybenzylidene)-5-chloro-1,3-dihydroindol-2-one | HCID 53704562 | 81% |
Reaction Steps
5-Chloro-2-oxindole (167 mg, 1 mmol) was condensed with 3-bromo-5-tert-butyl-4-hydroxybenzaldehyde (308.5 mg, 1.2 mmol) using method B to give 329 mg (81%) of 3-(3-bromo-5-tert-butyl-4-hydroxybenzylidene)-5-chloro-1,3-dihydroindol-2-one as a mixture of isomers.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689806B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-d1448677acde436da318603a5dd419b6 |
| Source note | uspto-grants-2004_02 |