HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120255Generated: October 30, 2026
HCID 9926167, compound → HCID 54373932, compound
https://huagongshe.com/reaction/2120255
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 9926167 | HCID 9926167 | — |
| Reactant | 4-(3-dimethylaminopropyl)-3,5-dimethyl-1H-pyrrole-2-carbaldehyde | HCID 21925758 | — |
| Catalyst | Pyrrolidine | HCID 31268 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54373932 | HCID 54373932 | 87% |
Reaction Steps
A mixture of 4-[2-(3-isopropyl-phenoxy)-ethyl]-1,3-dihydro-indol-2-one (28 mg, 0.095 mmol), 4-(3-dimethylamino-propyl)-3,5-dimethyl-1H-pyrrole-2-carbaldehyde (20 mg, 0.095 mmol) and 1 drop of pyrrolidine in 1.0 mL of ethanol was heated at 90° C. for 4 hours and cooled to room temperature. The precipitate was filtered, washed with cold ethanol and hexane, and dried in a vacuum oven overnight to give 40 mg (87%) of 3-[4-(3-dimethylamino-propyl)-3,5-dimethyl-1H-pyrrol-2-ylmethylene]-4-[2-(3-isopropyl-phenoxy)-ethyl]-1,3-dihydro-indol-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06689806B1 |
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| Source dataset | uspto-grants-2004_02 |
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| ORD ID | ord-6f856657282a47ad85a1794083f08c0c |
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| Source note | uspto-grants-2004_02 |
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