HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Benzenesulfonyl-1-benzyl-2-hydroxy-7-methyl-octyl)carbamic acid benzyl ester → 2-Amino-5-benzenesulfonyl-8-methyl-1-phenyl-nonan-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Benzenesulfonyl-1-benzyl-2-hydroxy-7-methyl-octyl)carbamic acid benzyl ester | HCID 69689188 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-5-benzenesulfonyl-8-methyl-1-phenyl-nonan-3-ol | HCID 69687892 | — |
Reaction Steps
To a solution of (4-benzenesulfonyl-1-benzyl-2-hydroxy-7-methyl-octyl)-carbamic acid benzyl ester in ethanol is added 10 mole % palladium hydroxide on carbon. The mixture is then shaken on a Parr shaker under 50 psi of hydrogen for approximately 18 h. The catalyst is filtered off and the solution concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689886B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-8a3374463e6f40f8942fca3a776f1109 |
| Source note | uspto-grants-2004_02 |