Tetrabutylammonium Fluoride → HCID 11384032, compound

HRID 2120429Notes

Reaction equation

[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:32]=[CH:33][C:34]=1[CH2:35][O:36][Si](C(C)(C)C)(C)C)[O:13][CH2:14][C:15]1[CH:16]=[C:17]([CH:21]([CH3:31])[CH2:22][CH2:23][CH2:24][C:25]([CH2:29][CH3:30])([OH:28])[CH2:26][CH3:27])[CH:18]=[CH:19][CH:20]=1)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:32]=[CH:33][C:34]=1[CH2:35][OH:36])[O:13][CH2:14][C:15]1[CH:16]=[C:17]([CH:21]([CH3:31])[CH2:22][CH2:23][CH2:24][C:25]([CH2:29][CH3:30])([OH:28])[CH2:26][CH3:27])[CH:18]=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 2724141Tetrabutylammonium Fluoride

HCID 23439912HCID 23439912, compound

Product 1

HCID 11384032HCID 11384032, compound

Procedure

In a manner similar to Example 3(i), by reacting 230 mg (0.36 mmol) of 7-{3-[3,4-bis-(tert-butyldimethylsilanyloxymethyl)phenoxymethyl]phenyl}-3-ethyloctan-3-ol with 1.2 ml of tetrabutylammonium fluoride, a colourless oil (m=110 mg; Y=75%) is obtained.

Workup

customa colourless oil (m=110 mg; Y=75%) is obtained

Sources & evidence

ORD record: ord-f4567744ba604d728fc79151b313ccdd
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06689922B1

Reaction notes

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