Methanol → HCID 10271985, compound

Participants

Reaction Steps

340 mg of (4E,6E)-7-(3-{2-[3,4-bis-(tert-butyldimethylsilanyloxymethyl)phenyl]ethyl}phenyl)-3-ethylocta-4,6-dien-3-ol (0.5 mmol) are dissolved in 10 ml of THF and 1.5 ml (1.5 mmol) of a tetrabutylammonium fluoride solution (1M in THF) are added dropwise. After 30 minutes, 10 ml of methanol are added and the mixture is concentrated under reduced pressure. After purification of the residue by chromatography on a silica column, a colourless oil is obtained (m=163 mg; Y=88%).

Provenance & Evidence